General Clinical Chemistry Analyzers and Accessories
AdipoGen 2-Heptyl-3-hydroxyl-4-quinolon
Chemical. CAS 108985-27-9. Formula C16H21NO2. MW 259.34. Synthetic. 2-heptyl-3-hydroxy-4-quinolone can function as an intercellular signal. Quorum sensing-regulated virulence factor used to induce and study the regulation of virulence genes such as those involved in iron scavenging. Quorum sensing is a signaling system used by bacteria to coordinate activity based upon their population density. The system involves the exchange of signaling molecules among bacteria via cell receptors.
Abcam Mitoglitazone (MSDC-0160), mTOT modulator.
Mitoglitazone (MSDC-0160), mTOT modulator.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Elvitegravir, quinolone HIV integrase inhibitor, 10MG
MW 447.9 Da, Purity >99%. Elvitegravir is an inhibitor of HIV integrase. It inhibits HIV integrase from HIV 1 IIIB (IC₅₀ = 0.7 nM), HIV 2 EHO (IC₅₀ = 2.8 nM) and HIV-2 ROD (IC₅₀ = 1.1 nM) in cell free assays. Elvitegravir blocks integration of HIV cDNA via inhibition of DNA strand transfer. Active against a range of HIV sub-types and against mulit-drug resistant clinical isolates. Potent (IC₅₀ range = 0.21 - 1.15 nM) HIV antiviral activity in various cell-based assays.
The product is subject to the following: Abcam Restricted Use Statement
Abcam BAY-299, TAF1 and BRD1 inhibitor, 25MG
MW 429.5 Da, Purity >98%. Potent and selective bromodomain inhibitor of TAF1 (IC₅₀ = 8-13 nM) and BRD1 (IC₅₀ = 6-67 nM). More than 30-fold selective versus BRD9 and ATAD2. More than 300-fold selective versus BRD4. Inhibits BRD1 (IC₅₀ = 0.58 μM) and TAF1 (IC₅₀ = 0.9 μM) binding to Histone H4 in cell-based assays; also inhibits BRD1 (IC₅₀ = 0.83 μM) and TAF1 (IC₅₀ = 1.4 μM) binding to Histone H3.3.
The product is subject to the following: Abcam Restricted Use Statement
Abcam BAY-299, TAF1 and BRD1 inhibitor, 5MG
MW 429.5 Da, Purity >98%. Potent and selective bromodomain inhibitor of TAF1 (IC₅₀ = 8-13 nM) and BRD1 (IC₅₀ = 6-67 nM). More than 30-fold selective versus BRD9 and ATAD2. More than 300-fold selective versus BRD4. Inhibits BRD1 (IC₅₀ = 0.58 μM) and TAF1 (IC₅₀ = 0.9 μM) binding to Histone H4 in cell-based assays; also inhibits BRD1 (IC₅₀ = 0.83 μM) and TAF1 (IC₅₀ = 1.4 μM) binding to Histone H3.3.
The product is subject to the following: Abcam Restricted Use Statement
Abcam V x -745, p38 alpha MAPK inhibitor, 5MG
MW 436.3 Da. Potent, selective p38 alpha MAPK inhibitor (IC₅₀ = 10 nM), with 20-fold selectivity over p38 beta and 1000-fold selectivity over closely related kinases, ERK1 and JNK1-3.
The product is subject to the following: Abcam Restricted Use Statement
Abcam FC 131, C x CR4 activation inhibitor, 5MG
MW 729.8 Da, Purity >95%. FC 131, CXCR4 activation inhibitor. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Abcam CUR 61414, Hedgehog signaling pathway antagonist, 5MG
MW 550.7 Da, Purity >98%. Novel, cell permeable Hedgehog signaling pathway antagonist (IC₅₀ = 100-200 nM). Selectively binds to smoothened (Smo) (Ki = 44 nM). Blocks the formation of and induces the regression of basaloid lesions in skin punches and shrinks UV-induced basaloid lesions in adult mouse skin. Inhibits proliferation and induces apoptosis in tumor cells without affecting non-tumor cells.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Dovitinib, class III-V receptor tyrosine kinase inhibitor, 25MG
MW 392.4 Da, Purity >99%. Potent, selective inhibitor of class III-V receptor tyrosine kinases (RTKs). Inhibits FLT3 (IC₅₀ = 1 nM), c-KIT (IC₅₀ = 2 nM), FGFR (IC₅₀ = 8 nM), VEGFR1/2/3 (IC₅₀ values are 10 nM, 13 nM and 8 nM respectively), PDGFRβ (IC₅₀ = 27 nM), and CSF-1R (IC₅₀ = 36 nM). Selectively blocks growth of B9 cells transformed by wild type, or activated mutant FGFR3. Induces apoptosis, or sensitizes cells to induction of apoptosis by other means in a variety of cancer cell lines.
The product is subject to the following: Abcam Restricted Use Statement
Abcam E7820, 5MG
MW 336.4 Da, Purity >=98%. A small molecule sulfonamide derivative with potential antiangiogenic and antitumor activities. E7820 inhibits angiogenesis by suppressing integrin alpha 2, a cell adhesion molecule expressed on endothelial cells. Inhibition of integrin alpha 2 leads to an inhibition of cell-cell interactions, endothelial cell-matrix interactions, vascular endothelial cell proliferation and angiogenesis.
The product is subject to the following: Abcam Restricted Use Statement
Abcam V-9302, 5MG
MW 538.7 Da, Purity >=98%. A competitive antagonist of transmembrane glutamine flux, that selectively targets the amino acid transporter ASCT2 (SLC1A5). V-9302 inhibits ASCT2-mediated glutamine uptake (IC₅₀ = 9.6 μM) in HEK-293 cells.
The product is subject to the following: Abcam Restricted Use Statement
Abcam IMR-1, 25MG
MW 353.4 Da, Purity =99%. Notch pathway inhibitor. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Roche Diagnostics ISE Sodium Electrode Bio HT Test kit for the Cedex Bio HT Analyzer | 1 piece
ISE Sodium Electrode Bio HT Test kit for the Cedex Bio HT Analyzer1 piece
Roche Diagnostics Multi-calibrator solution, Calibrator A Bio
This product is intended for calibration of quantitative assays of the Cedex Bio and Cedex Bio HT Analyzers for the following tests: Acetate (ACB, ACD) Glucose (GLC2B, GLC2D, GLC3B, GLC3D) Glutamate (GLUB, GLUD) Glycerol (GLYB, GLYD) IgG (IGGLB, IGGHB, IGGHD) Lactate (LAC2B, LAC2D) Phosphate (PHO2B, PHO2D) Total Protein (TP2B, TP2D) Use this calibrator as described in the instructions of the respective assay.
