General Clinical Chemistry Analyzers and Accessories
Abcam SB-525334, TGFBR1 inhibitor., 5MG
MW 343.4 Da, Purity >98%. Cell permeable, potent, selective transforming growth factor beta 1 receptor (ALK5) (IC₅₀ = 14.3 nM) and ALK4 (IC₅₀ = 58.5 nM) inhibitor, with no activity at ALK2, 3 and 6 (IC₅₀ > 10 μM). Blocks fibrosis and renal injury markers in a puromycin-induced nephritis model. Causes significant attenuation in Smad2/3 nuclear translocation and a decrease in CTGF-expressing cells, myofibroblast proliferation and type 1 collagen deposition resulting in an overall attenuation in bleomycin-induced pulmonary fibrosis.
The product is subject to the following: Abcam Restricted Use Statement
Roche Diagnostics Sodium Bio HT, 200 tests
Kit for determination of sodium. This product is intended for quantitative determination of sodium in aqueous solutions using the Cedex Bio HT Analyzer.
Roche Diagnostics Multi-calibrator solution, Calibrator A Bio
This product is intended for calibration of quantitative assays of the Cedex Bio and Cedex Bio HT Analyzers for the following tests: Acetate (ACB, ACD) Glucose (GLC2B, GLC2D, GLC3B, GLC3D) Glutamate (GLUB, GLUD) Glycerol (GLYB, GLYD) IgG (IGGLB, IGGHB, IGGHD) Lactate (LAC2B, LAC2D) Phosphate (PHO2B, PHO2D) Total Protein (TP2B, TP2D) Use this calibrator as described in the instructions of the respective assay.
Abcam Daclatasvir (BMS-790052), HCV NS5A protein inhibitor, 50MG
MW 738.9 Da, Purity =97%. Daclatasvir a potent, direct acting, small molecule inhbitor of HCV NS5A protein. It inhbibits replicons expressing a wide range of HCV genotypes with EC₅₀ values in the pM range (9 and 71 pM against the 1b and 2a genotypes, respectively). It also inhibits infection by the JFH-1 genotype 2a virus in cultured cells. Daclatasvir is thought to inhibit relication of the HCV viral genome by affecting the subcellular localization of HCV NS5A and preventing its incorporation into relication complexes. In HCV-infected Huh7 cells, Daclatasvir (1 nM) inhibits viral RNA synthesis and viron assembly. Daclatasvir displays moderate activity against the OAT1B1 (IC₅₀ = 1.5 μM) and OAT1B3 (IC₅₀ = 3.27 μM) organic anion transporters.
The product is subject to the following: Abcam Restricted Use Statement
Abcam TC 14012, Peptidomimetic C x CR4 antagonist, 10MG
MW 2066.4 Da, Purity >95%. TC 14012, Peptidomimetic CXCR4 antagonist. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Abcam AZD-5069, 5MG
MW 476.5 Da, Purity >=98%. A potent and reversible CXCR2 chemokine receptor antagonist with potential anti-inflammatory and antineoplastic activities. Upon administration, CXC chemokine receptor 2 antagonist AZD5069 directly binds to CXCR2 and inhibits its activation. This inhibits CXCR2-mediated signaling and may inhibit tumor cell proliferation in CXCR2-overexpressing tumor cells.
The product is subject to the following: Abcam Restricted Use Statement
Abcam HDM-201 (Siremadlin), 5MG
MW 555.4 Da, Purity >=98%. Potent and highly specific MDM-2/p53 inhibitor. It binds to human MDM2 protein with a picomolar Ki value (0.21 nM). It activates p53 and induces robust p53-dependent cell cycle arrest and apoptosis in human p53 wild-type tumor cells.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Umifenovir, 25MG
MW 477.4 Da, Purity >=95%. An indole derivative with broad-spectrum antiviral activity. It inhibits virus-mediated fusion with target membrane and blocks virus entry into target cells. It shows antiviral activity against many enveloped or non-enveloped RNA or DNA viruses with IC₅₀ values ranging from 0.41 to 16 uM. It (50 or 100 mg/kg/day) reduces mean pulmonary virus yields and the rate of mortality in mice infected with FLU-A (A/PR/8/34 H1N1). Molecular dynamics and structural analysis show that Umifenovir may target SARS-CoV-2 spike glycoprotein and may block its trimerization which will reduce cell adherence and virus entry.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Sunitinib, Free base, 1G
MW 398.5 Da, Purity >=99%. Sunitinib is a free base form of Sunitinib malate. A CSF-1 receptor kinase inhibitor .
The product is subject to the following: Abcam Restricted Use Statement
Nova Biomedical Corporation FLEX2 AUTOSMP STM ROTARY VALVE
Bioprofile Flex2 Autosampler STM Rotary Valve to 3-Way Valve Tubing Assembly.
Nova Biomedical Corporation Thermal Paper, pHOx Ultra and Prime only
Thermal Paper, pHOx Ultra and Prime only